Core Board Solution for Fluorescence Immunoassay

With the improvement of living standards, people are paying more and more attention to their own health problems, and family medical equipment has also received widespread attention. In the past, the fluorescent immunoassay analyzer was difficult to enter the home due to the large volume and slow output of the test results. How to break through this technology and improve the medical system? This article will detail the solution to improve the fluorescence immunoassay analyzer.

Introduction to Fluorescence Immunoassay

Fluorescence immunoassay analyzer is used for in vitro testing of hospitals. It mainly detects serum/plasma/ whole blood/urine samples of human body, assists in the diagnosis of myocardial injury, heart failure, acute coronary syndrome, cardiovascular inflammation, venous thromboembolism. , routine inflammation, identification of bacterial/viral infections, early detection and treatment of diseases such as acute and chronic kidney disease.

Development of fluorescent immunoassay analyzer

1. Development trend of laboratory medicine:

· Automation;

· Convenient;

· Accurate;

2, reduce the patient's time of treatment, reduce the economic pressure of patients

Rapid disease examination is an important factor affecting the recovery time. The timely and accurate test results are the guarantee for improving the quality of diagnosis and treatment. The individualized diagnosis for each patient's specific situation is the premise of clinical rational drug use, and is represented by fluorescence immunoassay analyzer. POCT (Rapid Detection) equipment is probably an effective way to achieve these goals.

3. At present, the hospital's automatic fluorescent immunoassay analyzer still dominates the hospital, and the handheld fluorescent immunometer will gradually occupy the mainstream of the market and gradually enter life.

Figure 1 Detection and Analysis Laboratory

Principle of fluorescent immunity

The working principle of the fluorescent immunoassay analyzer is that the lanthanide element is used as a fluorescent marker, and the use of such a substance has the characteristics of long fluorescence lifetime, prolonging the fluorescence time, and the natural background fluorescence of the short life is completely degraded before being measured, and the obtained signal is obtained. The fluorescence of the long-lived chelate is completely eliminated, thereby effectively eliminating the interference of the non-specific background fluorescence, and the effect of the reinforcing liquid is used to enhance the fluorescence signal so that the cerium ions are easily dissociated to form a chelating compound, and the illuminating article is irradiated with a pulse light source. After a short-term extinction, the electronic device controls the delay time, and after the non-specific background fluorescence decays, the long-lived fluorescence emitted by the sample is measured; due to the different molecular structure of the substance, the wavelength of the ultraviolet light absorbed and the wavelength of the emitted fluorescence are different. Gu can use this feature to measure the object.

Figure 2 fluorescence immunoassay analyzer

Fluorescent immune architecture and application areas

1. The basic structure of the automatic fluorescent immunoassay analyzer hardware:

Figure 3 hardware diagram of the automatic fluorescent immunoassay analyzer

2. Fluorescence immunoassay analyzers have been recognized as POCT (Rapid Detection) instruments by hospitals and families. Fluorescent immunoassays are also used in many other fields due to their rapid detection performance: IVD, food safety and fast Industries such as detection, rapid environmental testing, and animal and plant disease diagnosis have demand for fluorescent immunoassays.

Fluorescent Immunoassay Solution

For the fluorescent immunoassay analyzer ZLG Zhiyuan Electronics also introduced two different performance solutions of Cortex-A7/ Cortex-A8:

1) The small-volume core board can be used in different kinds of fluorescent immunoassay analyzers, and ample expansion interface is reserved. At the same time, in order to facilitate customer development, Zhiyuan Electronics provides thoughtful technical support and detailed technical development materials;

2) Cortex-A7/ Cortex-A8 also provides a wireless expansion solution. Through the MiniPcie interface, customers can choose WIFI, GPRS, 3G, 4G, ZigBee and other wireless solutions.

3) Rich hardware configuration;

4) The core board size is 30mm*48mm coin-sized, which is more suitable for handheld fluorescent immunoassay.

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